La Crosse, WI Commercial Property for Sale (66 Real Estate Listings)

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3055 State Road 16 -, La Crosse

$1,999,999

3055 State Road 16 -, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1902550

SELLER FINANCING available with adequate down payment! Prime opportunity to own highly desired real estate right along Highway 16. Own a turnkey building with a rock solid national tenant th...

eXp Realty LLCLogo

Pending
207 Causeway Blvd, La Crosse

$1,900,000

207 Causeway Blvd, La Crosse

2 Acres 30,000 SqFt Commercial MLS® # 1946959

This well-maintained, large commercial property offers exceptional versatility with a combination of shop and office space, ideal for a variety of business needs. Spacious Shop area with 14 ...

Coldwell Banker Commercial River ValleyLogo

Active
530 Lang Dr, La Crosse

$1,900,000

↑ $1,899,998

530 Lang Dr, La Crosse

0 Acres 14 SqFt Commercial MLS® # 1950952

PRIME NORTHSIDE LA CROSSE COMMERCIAL OPPORTUNITY.HIGH TRAFFIC LOCATION, TWO PARCELS, LONG-TERM LEASE IN PLACE.YOUR OPPORTUNITY TO INVEST IN A HIGH VISIBLE, INCOME-PRODUCING COMMERCIAL PROPER...

Cindy Gerke & AssociatesLogo

Active
529 4th St S 507-521-529, La Crosse

$1,600,000

529 4th St S 507-521-529, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1942561

YOUR BUSINESS WILL NOT GET MISSED ON THIS HIGH PROFILE 3/4 ACRE (+/-) DOWNTOWN CORNER IN THRIVING LA CROSSE BUSINESS DISTRICT! PLENTY OF DRIVE BY TRAFFIC/VISIBILITY, CONVENIENT LOCATION FOR...

RE/MAX ResultsLogo

Active
517 Copeland Ave, La Crosse

$1,200,000

517 Copeland Ave, La Crosse

1 Acres 7,240 SqFt Commercial MLS® # 1780187

Choice commercial building for sale with a choice central location. BUSINESS IS NOT FOR SALE! Building features wide open concepts and will adapt itself to a variety of uses. High ceiling...

Cindy Gerke & AssociatesLogo

Pending
2000 State Road 16 -, La Crosse

$1,150,000

2000 State Road 16 -, La Crosse

1 Acres 8,500 SqFt Commercial MLS® # 1891951

Extremely valuable ''A'' location with very high visibility. Owner of building is looking to retire and transition this extremely well cared for building to its new owner. Has finished fron...

Castle Realty, LLCLogo

Active
2006 State Road 16 -, La Crosse

$1,150,000

2006 State Road 16 -, La Crosse

1 Acres 10,300 SqFt Commercial MLS® # 1940983

Prime ''A'' location with exceptional visibility! Owner retiring and ready to pass along this well-maintained 10,300 sq ft property featuring updated lighting and durable standing-seam steel...

Castle Realty, LLCLogo

Active
423 Main St 425 & 427, La Crosse

$1,150,000

423 Main St 425 & 427, La Crosse

0 Acres 9,000 SqFt Commercial MLS® # 1949898

Own a cornerstone of downtown La Crosse including 423/425 & 427 Main St properties, offered together as a rare mixed-use investment package. Built in 1880, these historic buildings deliver c...

United Country Midwest Lifestyle Properties LLCLogo

Pending
4430 Mormon Coulee Rd, La Crosse

$950,000

4430 Mormon Coulee Rd, La Crosse

1 Acres 2,320 SqFt Commercial MLS® # 1945736

Commercial property with a 3 Bedroom house and 2 car garage located on the southside of La Crosse near Aldi's / Wendy's and Walmart. Corner lot at the stop lights with 4 curb cuts for ingre...

Gerrard-Hoeschler, REALTORSLogo

Active
1613 Chase St, La Crosse

$825,000

↓ $50,000

1613 Chase St, La Crosse

0 Acres 10,712 SqFt Commercial MLS® # 1940868

Nearly 11,000 sq ft of mixed use, versatile and impeccably kept multi-use building is now on the market! This property features two office spaces off of 16th St loaded with high end custom c...

eXp Realty LLCLogo

Active
422 Main St 424, La Crosse

$749,000

↓ $50,000

422 Main St 424, La Crosse

0 Acres 7,400 SqFt Commercial MLS® # 1944606

Discover a rare downtown La Crosse opportunity at 422-424 Main St. Formerly ''The Main'' event venue, this property blends historic character with modern versatility--featuring a large stage...

United Country Midwest Lifestyle Properties LLCLogo

Active
2128-2130 State Road 16 -, La Crosse

$689,000

2128-2130 State Road 16 -, La Crosse

0 Acres 6,298 SqFt Commercial MLS® # 1933103

A commercial location with visibility to 34,000 vehicles per day!! The light industrial zoning offers the possibility for many businesses in the space. The current clinic has several exam ro...

RE/MAX ResultsLogo

Active
2143 Ward Avenue, La Crosse

$649,000

2143 Ward Avenue, La Crosse

0 Acres 8,799 SqFt Commercial MLS® # 1995368

This remarkable commercial property is just what you need! Whether you're looking for an automotive shop, manufacturing business, commercial sales, or endless opportunities, this is for you....

Regional Multiple Listing Service of Minnesota Logo

Active
New
1720 Jackson St, La Crosse

$549,000

1720 Jackson St, La Crosse

0 Acres 2,346 SqFt Commercial MLS® # 1952929

Turn-key professional office or behavioral health facility with excellent visibility on Jackson St in La Crosse. This 2,346 SF bi-level building was completely renovated in 2023 and shows in...

Castle Realty, LLCLogo

Active
1123 3rd St S, La Crosse

$499,900

1123 3rd St S, La Crosse

0 Acres 1,700 SqFt Commercial MLS® # 1951244

This turnkey opportunity features a premier city establishment, with a reputation for excellence. Meticulously maintained and fully operational. The property reflects the deep commitment of ...

Gerrard-Hoeschler, REALTORSLogo

Active
518 Hagar St 629 Rose Street, La Crosse

$423,500

↓ $26,500

518 Hagar St 629 Rose Street, La Crosse

0 Acres 1,744 SqFt Commercial MLS® # 1931465

Great opportunity to own an established bar. Spacious horseshoe bar with multiple high-top tables for seating. Additional room that has 2 pool tables and gaming machines. Options for pool a...

Bi-State Realty & AppraisalsLogo

Active
411 3rd St S, La Crosse

$400,000

411 3rd St S, La Crosse

0 Acres 2,200 SqFt Commercial MLS® # 1902505

Investment opportunity awaits! This mixed commercial and residential property is conveniently located in highly trafficked and visible downtown La Crosse. This property is home to a trendy b...

@properties La CrosseLogo

Active
2042 George St, La Crosse

$135,000

2042 George St, La Crosse

0 Acres 1,250 SqFt Commercial MLS® # 1947114

Looking for that garage away from home? Look no further, 1250 +/- Sf 2 bay garage on the North side of La Crosse is perfect for all your projects!...

Coldwell Banker Commercial River ValleyLogo

La Crosse, WI Real Estate Statistics

Average Price $305K
Lowest Price $0
Highest Price $2.3M
Total Listings 149
Avg. Days On Market 188
Avg. Price/SQFT $1.1K

Property Types (active listings)


As of March 12, 2026 there are 66 active La Crosse, WI commercial real estate listings for sale with an average listing price of $273,181. The highest-priced commercial property listing is $1,999,999, while the lowest priced commercial property can be purchased for $0. La Crosse, WI Commercial properties for sale have an average price of $2,137 per square foot, based on commercial listings with an average of bedrooms, bathrooms, and 6,448 square feet of living space.

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