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La Crosse, WI Commercial Property for Sale

La Crosse, WI Commercial Property for Sale (76 Real Estate Listings)

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326 7th St S, La Crosse

$2,300,000

326 7th St S, La Crosse

0 Acres 13,026 SqFt Commercial MLS® # 1974555

30 Unit Apartment Building for Sale in Downtown La Crosse Wisconsin. This 3 story property consists of 12 One Bedroom Units and 18 Efficiency units and is Zoned R6. Most of the units have...

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Active
2974 Airport Rd, La Crosse

$2,200,000

2974 Airport Rd, La Crosse

2 Acres 16,080 SqFt Commercial MLS® # 1968027

Available for Sale or Lease! La Crosse's Airport Industrial Park encompasses 95 acres filled with 21 lots including Manufacturing Facilities Operational Hubs and Regional Shipping Faciliti...

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Active
300 2nd St S, La Crosse

$2,100,000

300 2nd St S, La Crosse

1 Acres 28,700 SqFt Commercial MLS® # 1957016

Radisson Center offers a rare downtown La Crosse redevelopment opportunity with exceptional flexibility and strong repositioning potential. Situated in the heart of the city's vibrant downto...

Coldwell Banker Commercial River ValleyLogo

Active
529 4th St S 507-521-529, La Crosse

$1,600,000

529 4th St S 507-521-529, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1942561

YOUR BUSINESS WILL NOT GET MISSED ON THIS HIGH PROFILE 3/4 ACRE (+/-) DOWNTOWN CORNER IN THRIVING LA CROSSE BUSINESS DISTRICT! PLENTY OF DRIVE BY TRAFFIC/VISIBILITY, CONVENIENT LOCATION FOR...

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Active
3055 State Road 16 -, La Crosse

$1,500,000

↓ $499,999

3055 State Road 16 -, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1902550

SELLER FINANCING available with adequate down payment! Prime opportunity to own highly desired real estate right along Highway 16. Own a turnkey building with a rock solid national tenant th...

eXp Realty LLCLogo

Active
New
319 Main St 321, La Crosse

$1,500,000

319 Main St 321, La Crosse

0 Acres 28,500 SqFt Commercial MLS® # 1976656

Historic Batavian Bank Building 319-321 Main Street Rare opportunity to own a piece of downtown La Crosse history (319 Main St & 321 Main St). Listed on the National Register of Historic Pl...

eXp Realty LLCLogo

Active
New
1411 Rose St, La Crosse

$1,500,000

1411 Rose St, La Crosse

1 Acres 4,818 SqFt Commercial MLS® # 1980346

High visibility 4 bay shop on 1.12 acres along Rose Street, one of La Crosse's busiest corridors. This turnkey property features in floor heat, multiple office spaces, and a clean, modern la...

eXp Realty LLCLogo

Active
517 Copeland Ave, La Crosse

$1,300,000

↑ $100,000

517 Copeland Ave, La Crosse

1 Acres 7,240 SqFt Commercial MLS® # 1780187

Choice commercial building for sale with a choice central location. BUSINESS IS NOT FOR SALE! Building features wide open concepts and will adapt itself to a variety of uses. High ceiling...

Cindy Gerke & AssociatesLogo

Active
2320 Cunningham St, La Crosse

$1,150,000

2320 Cunningham St, La Crosse

1 Acres 9,100 SqFt Commercial MLS® # 1973593

Commercial/Industrial property available with 2 buildings totaling 9100 SF on .86 acre. Located near Kwik Trip HQ in La Crosse's Interstate Industrial Park. Heavy Industrial zoning that al...

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Active
1434 Cass St 1-5, La Crosse

$1,125,000

↓ $75,000

1434 Cass St 1-5, La Crosse

0 Acres 10,300 SqFt Commercial MLS® # 1977028

1434 Cass Street is truly one of a kind. This historic property is packed with character, incredible architecture, turrets, and a ton of history. Currently set up as a 5-unit, but the real o...

eXp Realty LLCLogo

Active
1613 Chase St, La Crosse

$825,000

↓ $50,000

1613 Chase St, La Crosse

0 Acres 10,712 SqFt Commercial MLS® # 1940868

Rezoned Commercial recently! Nearly 11,000 sq ft of mixed use, versatile and impeccably kept multi-use building is now on the market! This property features two office spaces off of 16th St ...

eXp Realty LLCLogo

Active
4430 Mormon Coulee Rd, La Crosse

$800,000

↓ $150,000

4430 Mormon Coulee Rd, La Crosse

1 Acres 2,320 SqFt Commercial MLS® # 1945736

Commercial property with a 3 Bedroom house and 2 car garage located on the southside of La Crosse near Aldi's / Wendy's and Walmart. Corner lot at the stop lights with 4 curb cuts for ingre...

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Active
1101 Lacrosse St, La Crosse

$799,900

↓ $75,100

1101 Lacrosse St, La Crosse

0 Acres 2,200 SqFt Commercial MLS® # 1956084

An exceptional & rare opportunity to own a truly iconic establishment. Chuck's has long been a staple of the community-functioning seamlessly as a dive bar, neighborhood gathering spot, & co...

Realty of America, LLCLogo

Active
103 3rd St N, La Crosse

$660,000

103 3rd St N, La Crosse

0 Acres 3,838 SqFt Commercial MLS® # 1972137

Opportunity to own a premier downtown commercial property in one of the city's most established hospitality locations. With a long history as a successful pub and restaurant, this highly vis...

Coldwell Banker Commercial River ValleyLogo

Active
New
2128-2130 State Road 16 -, La Crosse

$649,000

2128-2130 State Road 16 -, La Crosse

0 Acres 6,298 SqFt Commercial MLS® # 1979179

A commercial location with visibility to 34,000 vehicles per day!! The light industrial zoning offers the possibility for many businesses in the space. The current clinic has several exam ro...

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Active
318 Pearl St, La Crosse

$550,000

↓ $49,000

318 Pearl St, La Crosse

0 Acres 2,600 SqFt Commercial MLS® # 1966885

Prime Commercial Space for Sale in the heart of Downtown La Crosse located on historic Pearl Street. Currently operating as a Tavern, this property can offer a wide variety of uses. High f...

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Active
1720 Jackson St, La Crosse

$499,000

↓ $50,000

1720 Jackson St, La Crosse

0 Acres 2,346 SqFt Commercial MLS® # 1952929

Turn-key professional office or behavioral health facility with excellent visibility on Jackson St in La Crosse. This 2,346 SF bi-level building was completely renovated in 2023 and shows in...

Castle Realty, LLCLogo

Active
New
1123 3rd St S, La Crosse

$485,000

1123 3rd St S, La Crosse

0 Acres 1,700 SqFt Commercial MLS® # 1977661

This turnkey opportunity features a premier city establishment, with a reputation for excellence. Meticulously maintained and fully operational. The property reflects the deep commitment of ...

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La Crosse, WI Real Estate Statistics

Average Price $305K
Lowest Price $0
Highest Price $2.3M
Total Listings 242
Avg. Days On Market 164
Avg. Price/SQFT $132

Property Types (active listings)


As of September 13, 2026 there are 76 active La Crosse, WI commercial real estate listings for sale with an average listing price of $320,966. The highest-priced commercial property listing is $2,300,000, while the lowest priced commercial property can be purchased for $0. La Crosse, WI Commercial properties for sale have an average price of $62 per square foot, based on commercial listings with an average of bedrooms, bathrooms, and 8,249 square feet of living space.

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