Appleton, WI Commercial Property for Sale (27 Real Estate Listings)

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1101 E South River Street, APPLETON

$8,990,000

1101 E South River Street, APPLETON

12 Acres 115,776 SqFt Commercial MLS® # 50307089

Prime Office Opportunity – 1111 E South River St, Appleton, WI Position your business for success with this premier office property located along the scenic South River in the heart of Appl...

Keller Williams Green BayRegional Multiple Listing Service of Minnesota Logo

ACTIVE
2810 N Roemer Road, Appleton

$2,978,860

2810 N Roemer Road, Appleton

31,690 SqFt Commercial MLS® # 22502339

Two manufacturing buildings in Appleton’s Northeast Business Park. Property Features • 2 loading docks; 4 drive-in doors • 5 bridge cranes: (1) 10-ton; (5) 5-ton • (6) 1-ton jib cra...

NAI PFEFFERLERegional Multiple Listing Service of Minnesota Logo

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New
2720 N Kesting Court, APPLETON

$2,195,000

2720 N Kesting Court, APPLETON

2 Acres 26,140 SqFt Commercial MLS® # 50308899

This spacious and versatile commercial property offers endless potential for a wide range of business uses. The main level features a spacious foyer area bordered by two wings—one with multi...

Coldwell Banker Real Estate GroupRegional Multiple Listing Service of Minnesota Logo

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5523 W Integrity Way, APPLETON

$1,600,000

5523 W Integrity Way, APPLETON

2 Acres 5,520 SqFt Commercial MLS® # 50306201

Walking distance from Costco. The location could not be any better for any business looking for high exposure. Being sold with all the office furniture, it is a turn-key operation. The recep...

Mark D Olejniczak Realty, Inc.Regional Multiple Listing Service of Minnesota Logo

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W6530 Pathfinder Drive Lot H & I, APPLETON

$1,400,000

↓ $50,000

W6530 Pathfinder Drive Lot H & I, APPLETON

0 Acres 7,000 SqFt Commercial MLS® # 50287674

Rare Opportunity to own 2 Airplane Hangars at the ATW airport, Appleton, WI. Owner Occupy or lease one or both buildings as an income property. -Gated Secure access -Easy in/out to airstri...

Berkshire Hathaway HS Fox Cities RealtyRegional Multiple Listing Service of Minnesota Logo

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New
2415 N Richmond Street, APPLETON

$825,000

2415 N Richmond Street, APPLETON

1 Acres 11,392 SqFt Commercial MLS® # 50302910

This impressive 11,000+ square foot commercial building is ideally situated on a highly trafficked street - on average 5400 cars daily, offering unparalleled visibility for business seeking ...

Seidl & Associates a div of Shorewest, RealtorsRegional Multiple Listing Service of Minnesota Logo

Active
New
1336 N Ballard Road, APPLETON

$800,000

1336 N Ballard Road, APPLETON

1 Acres 9,120 SqFt Commercial MLS® # 50299558

Successful Custom Cabinetry, Furniture and Commercial Cabinet Manufacturing Business is looking for a new owner. This Turnkey Business includes the Building, Equipment, Fixtures and Inventor...

Century 21 AffiliatedRegional Multiple Listing Service of Minnesota Logo

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New
W6471 Manitowoc Road, APPLETON

$399,000

W6471 Manitowoc Road, APPLETON

5 Acres 5,944 SqFt Commercial MLS® # 50287405

Whether you envision COMMERCIAL retail establishments, professional offices, or service-oriented ventures, this property provides the foundation for success. Positioned at a prime intersecti...

Coldwell Banker Real Estate GroupRegional Multiple Listing Service of Minnesota Logo

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N4899 County Road Ee, APPLETON

$374,900

N4899 County Road Ee, APPLETON

3 Acres 5,616 SqFt Commercial MLS® # 50313454

Beloved since 1955, Mer & Jackie’s Supper Club is a Fox Valley icon ready for its next chapter. Set on 2.75 acres at the well-known Five Corners, this 5,600 sq ft two-story building offers s...

Century 21 AffiliatedRegional Multiple Listing Service of Minnesota Logo

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New
1101 W Wisconsin Avenue, APPLETON

$314,900

1101 W Wisconsin Avenue, APPLETON

0 Acres 4,480 SqFt Commercial MLS® # 50315162

Excellent investment opportunity! The lower level features a vacant commercial space with a back storage/warehouse area, ideal for many business uses. The upper level offers a 2-bedroom, 1-b...

Epique RealtyRegional Multiple Listing Service of Minnesota Logo

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222 S State Street, APPLETON

$299,900

222 S State Street, APPLETON

0 Acres 2,400 SqFt Commercial MLS® # 50290762

Prime downtown location just 2 blocks off College Avenue. Walking distance to Dining, Shopping, Banking & more. Near the Justice and Expo Centers, PAC, local festivals including the Mile Of ...

LPT RealtyRegional Multiple Listing Service of Minnesota Logo

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New
400 S Linwood Avenue, APPLETON

$289,900

400 S Linwood Avenue, APPLETON

0 Acres 5,546 SqFt Commercial MLS® # 50309496

Exceptional investment opportunity at 400 S Linwood Ave, Appleton! This well-maintained commercial property features 16 versatile office suites, with 9 currently rented—providing immediate r...

Epique RealtyRegional Multiple Listing Service of Minnesota Logo

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New
1635 W Haskel Street, APPLETON

$225,000

↓ $24,900

1635 W Haskel Street, APPLETON

1 Acres 2,213 SqFt Commercial MLS® # 50309575

AWESOME LOCATION! START YOUR NEW BUSINESS HERE or relocate or expand! Former lawncare building w/extra space for vehicles that has a fenced around it. Ideal location with quick access to ...

Coldwell Banker Real Estate GroupRegional Multiple Listing Service of Minnesota Logo

Active
New
415 W Wisconsin Avenue, APPLETON

$225,000

415 W Wisconsin Avenue, APPLETON

0 Acres 2,890 SqFt Commercial MLS® # 50316915

Nearly 3,000 sq ft of versatile office & warehouse space, 415 W. Wisconsin presents a rare opportunity for a wide range of business uses. The main level is designed for productivity, offerin...

Keller Williams Fox CitiesRegional Multiple Listing Service of Minnesota Logo

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#ll - 200 W College Avenue, Appleton

$30,000

#ll - 200 W College Avenue, Appleton

0 Acres 49,934 SqFt Commercial MLS® # 1969070

Vibrant. Eclectic. Welcoming—WHAT’S NOT TO LOVE? Downtown Appleton hums with 25,000+ vehicles daily and ranks in Wisconsin’s top two business cities, a smart pick for your business. Wi...

Regional Multiple Listing Service of Minnesota Logo

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New
1600 N Casaloma Drive 1648,1660,1680, APPLETON

$0

1600 N Casaloma Drive 1648,1660,1680, APPLETON

3 Acres 24,510 SqFt Commercial MLS® # 50310517

For Lease. Excellent location! Just 3 spots remaining. Up to 7,000 sq ft available in total. 3512 sq ft built out as retail but can be modified to suit. Mostly medical in this property. Ver...

Besaw Properties, LtdRegional Multiple Listing Service of Minnesota Logo

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1280 S Van Dyke Road 5-6, APPLETON

$0

1280 S Van Dyke Road 5-6, APPLETON

1 Acres 6,000 SqFt Commercial MLS® # 50315519

FOR LEASE End Cap Commercial Unit: Approx 1,800 SF Flex Space with Interstate 41 Visibility! Flex commercial space with easy access. This 1,800 sq ft flex-use unit is available NOW and offe...

Beckman PropertiesRegional Multiple Listing Service of Minnesota Logo

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New
1101 W Wisconsin Avenue, APPLETON

$0

1101 W Wisconsin Avenue, APPLETON

0 Acres 4,480 SqFt Commercial MLS® # 50315745

For Lease. The lower level features a vacant commercial space with a back storage/warehouse area, ideal for many business uses....

Epique RealtyRegional Multiple Listing Service of Minnesota Logo

Appleton, WI Real Estate Statistics

Average Price $421K
Lowest Price $0
Highest Price $9M
Total Listings 325
Avg. Days On Market 2
Avg. Price/SQFT $182

Property Types (active listings)


As of December 6, 2025 there are 27 active Appleton, WI commercial real estate listings for sale with an average listing price of $775,832. The highest-priced commercial property listing is $8,990,000, while the lowest priced commercial property can be purchased for $0. Appleton, WI Commercial properties for sale have an average price of $54 per square foot, based on commercial listings with an average of bedrooms, bathrooms, and 26,171 square feet of living space.

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