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La Crosse, WI Commercial Property for Sale

La Crosse, WI Commercial Property for Sale (75 Real Estate Listings)

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326 7th St S, La Crosse

$2,300,000

326 7th St S, La Crosse

0 Acres 13,026 SqFt Commercial MLS® # 1974555

30 Unit Apartment Building for Sale in Downtown La Crosse Wisconsin. This 3 story property consists of 12 One Bedroom Units and 18 Efficiency units and is Zoned R6. Most of the units have...

Gerrard-Hoeschler, REALTORSLogo

Active
2974 Airport Rd, La Crosse

$2,200,000

2974 Airport Rd, La Crosse

2 Acres 16,080 SqFt Commercial MLS® # 1968027

Available for Sale or Lease! La Crosse's Airport Industrial Park encompasses 95 acres filled with 21 lots including Manufacturing Facilities Operational Hubs and Regional Shipping Faciliti...

Gerrard-Hoeschler, REALTORSLogo

Active
300 2nd St S, La Crosse

$2,100,000

300 2nd St S, La Crosse

1 Acres 28,700 SqFt Commercial MLS® # 1957016

Radisson Center offers a rare downtown La Crosse redevelopment opportunity with exceptional flexibility and strong repositioning potential. Situated in the heart of the city's vibrant downto...

Coldwell Banker Commercial River ValleyLogo

Active
1411 Rose St, La Crosse

$1,900,000

1411 Rose St, La Crosse

1 Acres 4,818 SqFt Commercial MLS® # 1955978

High visibility 4 bay shop on 1.12 acres along Rose Street, one of La Crosse's busiest corridors. This turnkey property features in floor heat, multiple office spaces, and a clean, modern la...

eXp Realty LLCLogo

Active
529 4th St S 507-521-529, La Crosse

$1,600,000

529 4th St S 507-521-529, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1942561

YOUR BUSINESS WILL NOT GET MISSED ON THIS HIGH PROFILE 3/4 ACRE (+/-) DOWNTOWN CORNER IN THRIVING LA CROSSE BUSINESS DISTRICT! PLENTY OF DRIVE BY TRAFFIC/VISIBILITY, CONVENIENT LOCATION FOR...

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3055 State Road 16 -, La Crosse

$1,500,000

↓ $499,999

3055 State Road 16 -, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1902550

SELLER FINANCING available with adequate down payment! Prime opportunity to own highly desired real estate right along Highway 16. Own a turnkey building with a rock solid national tenant th...

eXp Realty LLCLogo

Active
517 Copeland Ave, La Crosse

$1,200,000

517 Copeland Ave, La Crosse

1 Acres 7,240 SqFt Commercial MLS® # 1780187

Choice commercial building for sale with a choice central location. BUSINESS IS NOT FOR SALE! Building features wide open concepts and will adapt itself to a variety of uses. High ceiling...

Cindy Gerke & AssociatesLogo

Active
423 Main St 425 & 427, La Crosse

$1,150,000

423 Main St 425 & 427, La Crosse

0 Acres 9,000 SqFt Commercial MLS® # 1949898

Own a cornerstone of downtown La Crosse including 423/425 & 427 Main St properties, offered together as a rare mixed-use investment package. Built in 1880, these historic buildings deliver c...

United Country Midwest Lifestyle Properties LLCLogo

Active
2320 Cunningham St, La Crosse

$1,150,000

2320 Cunningham St, La Crosse

1 Acres 9,100 SqFt Commercial MLS® # 1973593

Commercial/Industrial property available with 2 buildings totaling 9100 SF on .86 acre. Located near Kwik Trip HQ in La Crosse's Interstate Industrial Park. Heavy Industrial zoning that al...

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Active
1613 Chase St, La Crosse

$825,000

↓ $50,000

1613 Chase St, La Crosse

0 Acres 10,712 SqFt Commercial MLS® # 1940868

Nearly 11,000 sq ft of mixed use, versatile and impeccably kept multi-use building is now on the market! This property features two office spaces off of 16th St loaded with high end custom c...

eXp Realty LLCLogo

Active
4430 Mormon Coulee Rd, La Crosse

$800,000

↓ $150,000

4430 Mormon Coulee Rd, La Crosse

1 Acres 2,320 SqFt Commercial MLS® # 1945736

Commercial property with a 3 Bedroom house and 2 car garage located on the southside of La Crosse near Aldi's / Wendy's and Walmart. Corner lot at the stop lights with 4 curb cuts for ingre...

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Active
1101 Lacrosse St, La Crosse

$799,900

↓ $75,100

1101 Lacrosse St, La Crosse

0 Acres 2,200 SqFt Commercial MLS® # 1956084

An exceptional & rare opportunity to own a truly iconic establishment. Chuck's has long been a staple of the community-functioning seamlessly as a dive bar, neighborhood gathering spot, & co...

Realty of America, LLCLogo

Active
103 3rd St N, La Crosse

$660,000

103 3rd St N, La Crosse

0 Acres 3,838 SqFt Commercial MLS® # 1972137

Opportunity to own a premier downtown commercial property in one of the city's most established hospitality locations. With a long history as a successful pub and restaurant, this highly vis...

Coldwell Banker Commercial River ValleyLogo

Active
318 Pearl St, La Crosse

$550,000

↓ $49,000

318 Pearl St, La Crosse

0 Acres 2,600 SqFt Commercial MLS® # 1966885

Prime Commercial Space for Sale in the heart of Downtown La Crosse located on historic Pearl Street. Currently operating as a Tavern, this property can offer a wide variety of uses. High f...

Gerrard-Hoeschler, REALTORSLogo

Active
1123 3rd St S, La Crosse

$499,900

1123 3rd St S, La Crosse

0 Acres 1,700 SqFt Commercial MLS® # 1951244

This turnkey opportunity features a premier city establishment, with a reputation for excellence. Meticulously maintained and fully operational. The property reflects the deep commitment of ...

Gerrard-Hoeschler, REALTORSLogo

Active
1720 Jackson St, La Crosse

$499,000

↓ $50,000

1720 Jackson St, La Crosse

0 Acres 2,346 SqFt Commercial MLS® # 1952929

Turn-key professional office or behavioral health facility with excellent visibility on Jackson St in La Crosse. This 2,346 SF bi-level building was completely renovated in 2023 and shows in...

Castle Realty, LLCLogo

Active
309 4th St S 311 313, La Crosse

$455,000

↓ $14,900

309 4th St S 311 313, La Crosse

0 Acres 3,600 SqFt Commercial MLS® # 1966710

Incredible opportunity to own high traffic real estate in downtown La Crosse. The possibilities are endless with roughly 12,000 vehicle impressions/day. Three business condo suites availa...

eXp Realty LLCLogo

Active
518 Hagar St 629 Rose Street, La Crosse

$399,900

↓ $23,600

518 Hagar St 629 Rose Street, La Crosse

0 Acres 1,744 SqFt Commercial MLS® # 1931465

Great opportunity to own an established bar. Spacious horseshoe bar with multiple high-top tables for seating. Additional room that has 2 pool tables and gaming machines. Options for pool a...

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La Crosse, WI Real Estate Statistics

Average Price $299K
Lowest Price $0
Highest Price $2.3M
Total Listings 237
Avg. Days On Market 91
Avg. Price/SQFT $136

Property Types (active listings)


As of August 8, 2026 there are 75 active La Crosse, WI commercial real estate listings for sale with an average listing price of $297,149. The highest-priced commercial property listing is $2,300,000, while the lowest priced commercial property can be purchased for $0. La Crosse, WI Commercial properties for sale have an average price of $60 per square foot, based on commercial listings with an average of bedrooms, bathrooms, and 7,484 square feet of living space.

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