La Crosse, WI Commercial Property for Sale (70 Real Estate Listings)

Sort by:
Active
1707 Main, La Crosse

$2,400,000

↓ $500,000

1707 Main, La Crosse

1 Acres 53,603 SqFt Commercial MLS® # 1847137

CHARMING, HISTORICAL BRICK BUILDING ON 1.2 ACRES IN THE HEART OF LA CROSSE'S SOUTHSIDE, 1/2 BLOCK FROM UNIVERSITY OF WISCONSIN LA CROSSE. THIS PROPERTY HAS BEEN WELL MAINTAINED, MECHANICALS/...

RE/MAX ResultsLogo

Active
3055 State Road 16, La Crosse

$1,999,999

↓ $300,001

3055 State Road 16, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1902550

Prime opportunity to own highly desired real estate right along Highway 16. Own a turnkey building with a rock solid national tenant that has been a pillar restaurant in the community for de...

eXp Realty LLCLogo

Active
2809 Larson 2815, La Crosse

$1,875,000

↓ $625,000

2809 Larson 2815, La Crosse

2 Acres 19,584 SqFt Commercial MLS® # 1900460

Industrial income property with three distinct rental spaces. Currently two spaces currently leased with additional approximately 5,000 square foot area available for additional tenant. Grea...

RE/MAX ResultsLogo

Active
507 4th 521-529, La Crosse

$1,600,000

507 4th 521-529, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1898756

YOUR BUSINESS WILL NOT GET MISSED ON THIS HIGH PROFILE 3/4 ACRE (+/-) DOWNTOWN CORNER IN THRIVING LA CROSSE BUSINESS DISTRICT! PLENTY OF DRIVE BY TRAFFIC/VISIBILITY, CONVENIENT LOCATION FOR...

RE/MAX ResultsLogo

Active
New
2803 Losey Boulevard S, La Crosse

$1,275,000

2803 Losey Boulevard S, La Crosse

1 Acres 7,000 SqFt Commercial MLS® # 1587810

Through no fault of their own, this exceptional opportunity is back on the market! This freestanding retail building offers 7,000 square feet of versatile space, perfect for a variety of bus...

Team TrilliumRegional Multiple Listing Service of Minnesota Logo

Active
517 Copeland, La Crosse

$1,200,000

517 Copeland, La Crosse

1 Acres 7,240 SqFt Commercial MLS® # 1780187

Choice commercial building for sale with a choice central location. BUSINESS IS NOT FOR SALE! Building features wide open concepts and will adapt itself to a variety of uses. High ceiling...

Cindy Gerke & AssociatesLogo

Active
2212 Rose Street, La Crosse

$849,999

↓ $125,001

2212 Rose Street, La Crosse

1 Acres 2,750 SqFt Commercial MLS® # 1905051

New Opportunity to Own a large eat in restaurant location that was formally a Pizza Hut and a staple to the North Side of La Crosse/Onalaska. Close access to I-90 and Highway 35. Traffic C...

Coldwell Banker Commercial River ValleyLogo

Active
301 - 313 4th, La Crosse

$849,900

301 - 313 4th, La Crosse

6,633 SqFt Commercial MLS® # 1901805

Great opportunity to own up to 6600 sqft on one of the highest trafficked street in La Crosse. Traffic count of almost 9,000. Property consists of 5 tax parcels that can be completely open...

eXp Realty LLCLogo

Active
103 3rd 227 Main, La Crosse

$785,000

↓ $50,000

103 3rd 227 Main, La Crosse

0 Acres 4,736 SqFt Commercial MLS® # 1906313

SUPER LOCATION WITH EXCEPTIONAL EXPOSURE IN HISTORIC DOWNTOWN LA CROSSE: PRIOR DUBLIN SQUARE LOCATION, EXPOSURE TO 3RD AND MAIN STREETS W/PLENTY OF BOTH FOOT & CAR TRAFFIC. SOLID/NEWER CONS...

RE/MAX ResultsLogo

Active
316-318 Pearl, La Crosse

$699,000

316-318 Pearl, La Crosse

0 Acres 2,800 SqFt Commercial MLS® # 1913466

Are you an Entrepreneur searching for that PRIME location for your next Tavern and would like to own a piece of Downtown La Crosse Wisconsin market? Located between two major highways with...

Gerrard-Hoeschler, REALTORSLogo

Active
2143 Ward Avenue, La Crosse

$649,000

↓ $16,000

2143 Ward Avenue, La Crosse

0 Acres 8,799 SqFt Commercial MLS® # 1995368

This remarkable commercial property is just what you need! Whether you're looking for an automotive shop, manufacturing business, commercial sales, or endless opportunities, this is for you....

Regional Multiple Listing Service of Minnesota Logo

Active
1102 Island, La Crosse

$599,000

↓ $40,000

1102 Island, La Crosse

0 Acres 4,900 SqFt Commercial MLS® # 1895258

Rare opportunity for an auto shop location with two large bays ready for your new business or business relocation. Plenty of parking with easy access off Lang Drive. Waiting area, separate o...

Coldwell Banker Commercial River ValleyLogo

Active
1123 3rd, La Crosse

$599,000

1123 3rd, La Crosse

0 Acres 1,700 SqFt Commercial MLS® # 1886135

Exceptionally well maintained La Crosse Bar & Grill For Sale! This Business has been well maintained and operated over the years, the Owner's have put their heart and soul into every detail...

Gerrard-Hoeschler, REALTORSLogo

Active
425 Rose 51, La Crosse

$559,000

425 Rose 51, La Crosse

0 Acres 5,051 SqFt Commercial MLS® # 1904333

Arneson Mini Storage on La Crosse's northside is for sale. This complex is well maintained, great location and always full. There are also 3 billboards that are included with this sale each...

Cindy Gerke & AssociatesLogo

Active
406 Jackson, La Crosse

$530,000

406 Jackson, La Crosse

0 Acres 2,088 SqFt Commercial MLS® # 1906730

This is a perfect location and layout for numerous types of businesses. 7 private offices in a size range of 12 x 11. 21 x 12 reception area with counter and cabinet area for receptionists. ...

RE/MAX ResultsLogo

Active
1221 La Crosse, La Crosse

$525,000

↓ $24,000

1221 La Crosse, La Crosse

0 Acres 1,344 SqFt Commercial MLS® # 1884972

Amazing opportunity to be on one of the prominent intersections in La Crosse. Over 36,000 vehicles per day passing by as well as significant foot traffic to UWL. The site offers ample parkin...

RE/MAX ResultsLogo

Active
309 - 313 4th, La Crosse

$446,900

309 - 313 4th, La Crosse

3,615 SqFt Commercial MLS® # 1901807

Great opportunity to own up to 3615 sqft on one of the highest trafficked streets in La Crosse. Traffic count of almost 9,000. Property consists of 3 tax parcels that can be completely ope...

eXp Realty LLCLogo

Active
1132 Caledonia, La Crosse

$439,900

1132 Caledonia, La Crosse

0 Acres 3,840 SqFt Commercial MLS® # 1905008

Great balance of storage and warehouse with large office space and partial basement. Half bath in the office and half bath in the shop. Improvements over the last two years include: Newer HV...

RE/MAX ResultsLogo

La Crosse, WI Real Estate Statistics

Average Price $284K
Lowest Price $0
Highest Price $2.4M
Total Listings 116
Avg. Days On Market 15
Avg. Price/SQFT $100

Property Types (active listings)


As of April 19, 2025 there are 70 active La Crosse, WI commercial real estate listings for sale with an average listing price of $279,811. The highest-priced commercial property listing is $2,400,000, while the lowest priced commercial property can be purchased for $0. La Crosse, WI Commercial properties for sale have an average price of $61 per square foot, based on commercial listings with an average of bedrooms, bathrooms, and 4,566 square feet of living space.

Contact Us

Provide a valid email address.
Newsletter consent