La Crosse County, WI Commercial Property for Sale (122 Real Estate Listings)

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W2658 State Road 33 -, Greenfield

$5,000,000

W2658 State Road 33 -, Greenfield

8 Acres 110,000 SqFt Commercial MLS® # 1902543

Historic Multi-Unit Healthcare/Assisted Living/Memory Care Facility with Stunning Views. Perched atop one of the region's most beautiful ridges, this four-story historic assisted living faci...

Gerrard-Hoeschler, REALTORSLogo

Active
W7665 Sylvester Rd, Holland

$4,975,000

W7665 Sylvester Rd, Holland

160 Acres 10,000 SqFt Commercial MLS® # 1905593

This is a rare opportunity to own an iconic, successful golf course and restaurant that combines the beauty of Holmen, WI with a thriving business. Whether you're a passionate golfer, an exp...

Coldwell Banker Commercial River ValleyLogo

Active
3340 S Kinney Coulee Road, Onalaska

$3,699,000

3340 S Kinney Coulee Road, Onalaska

5 Acres 15,000 SqFt Commercial MLS® # 7118440

Exceptional and rare 5-acre commercial parcel with 425± feet of prime I-90 frontage, offering outstanding visibility at interstate elevation! Located near the I-90 & Hwy 16 interchange and l...

Edina Realty, Inc.Regional Multiple Listing Service of Minnesota Logo

Active
N5550 County Rd Z, Onalaska

$2,550,000

↓ $150,000

N5550 County Rd Z, Onalaska

2 Acres 17,640 SqFt Commercial MLS® # 1954054

No need to worry about these stunning commercial buildings, completed in early 2025 and ready for your business to move right in. Building 1 features an impressive showroom with office space...

Coulee Real Estate & Property Management LLCLogo

Pending
New
326 7th St S, La Crosse

$2,300,000

326 7th St S, La Crosse

0 Acres 13,026 SqFt Commercial MLS® # 1974555

30 Unit Apartment Building for Sale in Downtown La Crosse Wisconsin. This 3 story property consists of 12 One Bedroom Units and 18 Efficiency units and is Zoned R6. Most of the units have...

Gerrard-Hoeschler, REALTORSLogo

Active
2974 Airport Rd, La Crosse

$2,200,000

2974 Airport Rd, La Crosse

2 Acres 16,080 SqFt Commercial MLS® # 1968027

Available for Sale or Lease! La Crosse's Airport Industrial Park encompasses 95 acres filled with 21 lots including Manufacturing Facilities Operational Hubs and Regional Shipping Faciliti...

Gerrard-Hoeschler, REALTORSLogo

Active
300 2nd St S, La Crosse

$2,100,000

300 2nd St S, La Crosse

1 Acres 28,700 SqFt Commercial MLS® # 1957016

Radisson Center offers a rare downtown La Crosse redevelopment opportunity with exceptional flexibility and strong repositioning potential. Situated in the heart of the city's vibrant downto...

Coldwell Banker Commercial River ValleyLogo

Pending
W7153 County Road Z -, Onalaska

$2,100,000

W7153 County Road Z -, Onalaska

3 Acres 17,280 SqFt Commercial MLS® # 1976325

Waterfront Investment Property on Lake Onalaska. 3 Buildings containing four 2 Bed, 2 Bath, 1,440 sf units each. Each unit has a range/oven, refrigerator, dishwasher, laundry hookups and ...

Gerrard-Hoeschler, REALTORSLogo

Active
529 4th St S 507-521-529, La Crosse

$1,600,000

529 4th St S 507-521-529, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1942561

YOUR BUSINESS WILL NOT GET MISSED ON THIS HIGH PROFILE 3/4 ACRE (+/-) DOWNTOWN CORNER IN THRIVING LA CROSSE BUSINESS DISTRICT! PLENTY OF DRIVE BY TRAFFIC/VISIBILITY, CONVENIENT LOCATION FOR...

RE/MAX ResultsLogo

Active
3055 State Road 16 -, La Crosse

$1,500,000

↓ $499,999

3055 State Road 16 -, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1902550

SELLER FINANCING available with adequate down payment! Prime opportunity to own highly desired real estate right along Highway 16. Own a turnkey building with a rock solid national tenant th...

eXp Realty LLCLogo

Active
New
319 Main St 321, La Crosse

$1,500,000

319 Main St 321, La Crosse

0 Acres 28,500 SqFt Commercial MLS® # 1976656

Historic Batavian Bank Building 319-321 Main Street Rare opportunity to own a piece of downtown La Crosse history (319 Main St & 321 Main St). Listed on the National Register of Historic Pl...

eXp Realty LLCLogo

Active
517 Copeland Ave, La Crosse

$1,300,000

↑ $100,000

517 Copeland Ave, La Crosse

1 Acres 7,240 SqFt Commercial MLS® # 1780187

Choice commercial building for sale with a choice central location. BUSINESS IS NOT FOR SALE! Building features wide open concepts and will adapt itself to a variety of uses. High ceiling...

Cindy Gerke & AssociatesLogo

Active
2320 Cunningham St, La Crosse

$1,150,000

2320 Cunningham St, La Crosse

1 Acres 9,100 SqFt Commercial MLS® # 1973593

Commercial/Industrial property available with 2 buildings totaling 9100 SF on .86 acre. Located near Kwik Trip HQ in La Crosse's Interstate Industrial Park. Heavy Industrial zoning that al...

ACRE PropertiesLogo

Active
1434 Cass St 1-5, La Crosse

$1,125,000

↓ $75,000

1434 Cass St 1-5, La Crosse

0 Acres 10,300 SqFt Commercial MLS® # 1977028

1434 Cass Street is truly one of a kind. This historic property is packed with character, incredible architecture, turrets, and a ton of history. Currently set up as a 5-unit, but the real o...

eXp Realty LLCLogo

Active
3220 Kinney Coulee Rd S, Onalaska

$950,000

3220 Kinney Coulee Rd S, Onalaska

1 Acres 12,000 SqFt Commercial MLS® # 1958117

Unlock the potential of this versatile warehouse/storage building, perfectly suited for a variety of business uses and already configured for a doggy daycare and grooming operation. This pro...

Castle Realty, LLCLogo

Active
234 Leonard St N, West Salem

$850,000

↓ $45,000

234 Leonard St N, West Salem

0 Acres 3,561 SqFt Commercial MLS® # 1951677

Established boutique winery opportunity! This unique offering includes a fully operational winery that manufactures and sells its own wines, serves appetizers, and hosts intimate events for ...

RE/MAX ResultsLogo

Active
1613 Chase St, La Crosse

$825,000

↓ $50,000

1613 Chase St, La Crosse

0 Acres 10,712 SqFt Commercial MLS® # 1940868

Rezoned Commercial recently! Nearly 11,000 sq ft of mixed use, versatile and impeccably kept multi-use building is now on the market! This property features two office spaces off of 16th St ...

eXp Realty LLCLogo

Pending
601 Mchugh Rd, Holmen

$800,000

601 Mchugh Rd, Holmen

1 Acres 3,846 SqFt Commercial MLS® # 1947075

Presenting a rare opportunity to acquire a meticulously maintained, high-visibility professional center located in fast growing Holmen community. Whether you are looking for a stable additi...

RE/MAX ResultsLogo

La Crosse County, WI Real Estate Statistics

Average Price $312K
Lowest Price $0
Highest Price $5M
Total Listings 856
Avg. Days On Market 170
Avg. Price/SQFT $168

Property Types (active listings)


As of September 10, 2026 there are 122 active La Crosse County, WI commercial real estate listings for sale with an average listing price of $406,483. The highest-priced commercial property listing is $5,000,000, while the lowest priced commercial property can be purchased for $0. La Crosse County, WI Commercial properties for sale have an average price of $69 per square foot, based on commercial listings with an average of bedrooms, bathrooms, and 7,548 square feet of living space.

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